MOTS-c
A 16-block peptide your own mitochondria make. Studied for how muscles use sugar.
Most of the evidence○ Animal / lab only
01
What it's made of
16Blocks
MRWQEMGYIFYPRKLR
M R W Q E M G Y I F Y P R K L R. All 16 are standard amino acids.
Load it in the Peptide builder →02
Where it comes from
Made by your mitochondria, the power plants inside your cells. Discovered in 2015 by a lab at the University of Southern California.
03
What it's studied for
- ○ Animal / lab only
Blood sugar and weight: in mice on a high-fat diet, it reduced weight gain and improved insulin sensitivity.
- ○ Animal / lab only
Fitness with age: older mice given MOTS-c did better on physical tests.
- ◐ Reported
Exercise raises your own MOTS-c levels. That was observed in people, not tested by giving it as a drug.
Studied for ≠ proven to work. Check the stamp.
04
What we don't know
- ?
I found no published results from giving MOTS-c to people.
- ?
"Exercise in a bottle" claims online go far beyond the evidence.
05
Status
- Not approved by any health regulator for use in people.
- Banned in sport at all times (World Anti-Doping Agency, metabolic modulators).
07
Words to know
Mitochondria = The parts of your cells that turn food into energy.Insulin sensitivity = How well your cells respond to insulin and take in sugar.